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Qual Saf Health Care 2004;13:181-185 doi:10.1136/qshc.2003.008334
  • Original Article

Indicators for preventable drug related morbidity: application in primary care

  1. C J Morris1,
  2. S Rodgers2,
  3. V S Hammersley2,
  4. A J Avery2,
  5. J A Cantrill1
  1. 1School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, UK
  2. 2Division of General Practice, University of Nottingham, Nottingham, UK
  1. Correspondence to:
 Dr C J Morris
 The Drug Usage and Pharmacy Practice Group, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester M13 9PL, UK; caroline.j.morrisman.ac.uk
  • Accepted 19 December 2003

Abstract

Aim: To apply in practice a series of validated indicators for preventable drug related morbidity (PDRM).

Design: A pilot study to identify retrospectively potential PDRM events over a 2 year 3 month time frame using the MIQUEST computer software program.

Subjects and setting: The electronic patient record of all patients aged 18 years and over in nine English general practices.

Outcome measures: The number of potential PDRM events identified, as defined by the indicators.

Results: Five hundred and seven potential PDRM events were identified from 49 658 electronic patient records, giving an overall incidence of 1.0%. A small number of the indicators (nā€Š=ā€Š4) accounted for approximately 60% of the events, while for many indicators few events were identified. The most common events related to the use of non-steroidal anti-inflammatory drugs in patients with congestive heart failure or hypertension, lack of monitoring in patients prescribed angiotensin converting enzyme inhibitors, and the use of hypnotic-anxiolytic agents.

Conclusions: A small number of indicators contributed to the majority of the PDRM events. Interrogation of electronic patient records in primary care using computerised queries shows potential for detecting PDRM.

Footnotes

  • See editorial commentary, p 170

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